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wiki:gynaecology:polycystic_ovary_syndrome [2020/06/16 08:12] – dj | wiki:gynaecology:polycystic_ovary_syndrome [2020/06/18 08:07] (current) – removed dj | ||
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- | =====Polycystic Ovary Syndrome===== | ||
- | Exact pathophysiology = unclear | ||
- | *often have raised testosterone | ||
- | *inappropriate gonadotrophin secretion - probably as a result of ovarian dysfunction rather than cause | ||
- | *most common hormonal abnormalities: | ||
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- | Diagnostic criteria have varied over the years and vary according to body meeting! Include the following: | ||
- | *evidence of ovarian dysfunction | ||
- | *exclusion of other disorders - eg other hormonal causes (Hypothyroidism, | ||
- | *biochemical evidence of hyperandrogenism | ||
- | *?USS evidence | ||
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- | Major features | ||
- | *menstrual dysfunction - usually a chronic pattern | ||
- | *anovulation | ||
- | *signs of hyperandrogenism - male hair distribution, | ||
- | *~50% are obese | ||
- | *Acanthosis nigricans - possibly due to insulin resistance | ||
- | *Hypertension | ||
- | *chronic pelvic pain | ||
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- | treatments aimed at so-called metabolic derangements, | ||
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- | **References include: | ||
- | https:// | ||
- | https:// | ||