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| wiki:gynaecology:polycystic_ovary_syndrome [2020/06/16 18:47] – dj | wiki:gynaecology:polycystic_ovary_syndrome [2020/06/18 10:07] (current) – removed dj | ||
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| - | =====Polycystic Ovary Syndrome===== | ||
| - | Exact pathophysiology = unclear | ||
| - | *often have raised testosterone | ||
| - | *inappropriate gonadotrophin secretion - probably as a result of ovarian dysfunction rather than cause | ||
| - | *most common hormonal abnormalities: | ||
| - | |||
| - | Diagnostic criteria have varied over the years and vary according to authority group! Include the following: | ||
| - | *evidence of ovarian dysfunction | ||
| - | *exclusion of other disorders - eg other hormonal causes (Hypothyroidism, | ||
| - | *biochemical evidence of hyperandrogenism | ||
| - | *?USS evidence | ||
| - | |||
| - | Major features | ||
| - | *menstrual dysfunction - usually a chronic pattern | ||
| - | *anovulation | ||
| - | *signs of hyperandrogenism - male hair distribution, | ||
| - | *~50% are obese | ||
| - | *Acanthosis nigricans - possibly due to insulin resistance | ||
| - | *Hypertension | ||
| - | *chronic pelvic pain | ||
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| - | treatments aimed at so-called metabolic derangements, | ||
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| - | ---- | ||
| - | **References include: | ||
| - | https:// | ||
| - | https:// | ||