===== Adrenal Crisis ===== ===common causes:=== * addison's disease * chronic steroid use * Waterhouse-Friedrichson syndrome (adrenal infarction due to DIC) * Pituitary apoplexy (pit infarction esp post partum, DIC) * Oncology - checkpoint inhib immunotherapy * Look for precipitants: -infection, trauma, pregnancy, reduced steroid use. Initiation of carbamazepine, etomidate, phenytoin etc ===presentation:=== * Vasodilatory shock esp refractory to fluid * N,V, abdo pain, fever, delirium ===Investigations:=== * low Na+, high K+, low Glu **NB - It is a Dx of exclusion. Rapid response to steroid is supportive of Dx ===Management:=== * look for triggers and treat * hydrocortisone esp if known adrenal insufficiency * dexamethasone - ??? esp if not known insufficiency - check * supportive