=====Leptospirosis===== [{{ :wiki:infection:f2.large_1_.jpg?400|**//Biphasic nature of illness and testing//**}}] *a zoonosis of protean manifestations *spectrum of symptoms is extremely broad *vast majority asymptomatic or mild *febrile illness of sudden onset. *Other: chills, headache, myalgia, abdominal pain, conjunctival suffusion, and less often a skin rash. *if present, rash is often transient, lasting less than 24/24. This anicteric syndrome usually lasts ~1/52, and resolution coincides with the appearance of antibodies. *The fever may be biphasic and may recur after a remission of 3 to 4 days. *headache is often severe, with retro-orbital pain and photophobia. *Myalgia affecting the lower back, thighs, and calves is often intense ==References include:== [[https://cmr.asm.org/content/14/2/296|Am Soc for Micro: Leptospirosis review 2001]]\\