=====Skin & Wounds===== ====Generalised itchy skin with rash==== *Chronic renal insufficiency *Cholestasis *Iron deficiency *Polycythaemia vera *Hyperthyroidism *Lymphoma *Diabetic neuropathy *Drug-induced (eg, opioid, chloroquine, vancomycin flushing) *Chronic pruritus of unknown origin ====Kawasaki disease==== most prominent cause of acquired coronary artery disease in childhood.\\ *also known as mucocutaneous lymph node syndrome, is an acute, systemic vasculitis of small- and medium-sized arteries that predominantly affects patients younger than five years. *Transthoracic echocardiography is the diagnostic imaging modality of choice to screen for coronary aneurysms, *Treatment for acute disease is intravenous immunoglobulin and aspirin. Classic (typical) Kawasaki disease is a clinical diagnosis. Based on the presence of a fever lasting 5/7 or more plus four out of five: -bilateral conjunctival injection -oral changes such as cracked and erythematous lips and strawberry tongue -cervical lymphadenopathy -extremity changes such as erythema or palm and sole desquamation (usually weeks 2, 3) -polymorphous rash. incomplete (atypical) - 2 or 3 findings [[https://www.aafp.org/pubs/afp/issues/2015/0315/p365.html#:~:text=Classic%20Kawasaki%20disease%20is%20diagnosed%20when%20patients%20have%20fever%20for,1%2C7%E2%80%9312%20).|Dx and Mx Kawasaki disease AFP 2015]] ====Pruritis in pregnancy==== {{ :wiki:pruritis_in_preg.jpg?400|}} ===Prurigo=== *intensely itchy spots - c/w pruritis in which there are no primary skin lesions *Primary prurigo lesions are dome-shaped or warty looking papules. *Secondary prurigo lesions are scratched papules which may become scaly, thick, darkened and scarring ***nodular prurigo** - very itchy firm lumps *strong FHx of atopic dermatitis *cause unknown *very difficult to treat [{{:wiki:nodular_prurigo.jpg?200|**//Nodular prurigo//**}}] [{{:wiki:nodular_prurigo2.jpg?200|**//Nodular prurigo//**}}] ---- ===Dog and cat bites=== *general cleaning and debridement where appropriate *generally should be left to heal by primary intention *puncture wounds should be cleaned after removal of any FB (eg teeth) where relevant and left open *tetanus IgG, booster and antibiotics should be considered *antibiotics especially if deep puncture or potential breach of tendon sheath or joint ===Tetanus=== {{ :wiki:tetanus_information_for_health_professionals_2019.pdf |}} ==References include:== https://dermnetnz.org/topics/nodular-prurigo/\\ https://dermnetnz.org/topics/differential-diagnosis-of-itchy-skin/\\ https://cks.nice.org.uk/topics/bites-human-animal/management/managing-a-cat-or-dog-bite/\\ [[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860924/#:~:text=Although%20most%20cases%20of%20pruritus,and%20atopic%20eruption%20of%20pregnancy.|Can Fam Phys - Pruritis in preg 2013]]\\