Pericarditis

  • usually viral (esp Coxsackie) but may be other infections
  • idiopathic
  • uraemia
  • neoplastic, paraneoplastic and post Rx eg. radiotherapy
  • post MI (Dressler's syndrome)

Pain

  • typically retrosternal but may radiate to trapezius M area
  • typically pleurtic
  • typically worse supine, better upright and leaning forward

Typical ECG changes - widespread concave upwards ST elevation & PR elevation with reciprocal ST depression and PR elevation in aVR which usually normalises from around 3/52

Management
  • analgesia - NSAIDs, aspirin is especially good
  • colchicine - some evidence to suggest it reduces recurrence
  • steroids if contra-indications to NSAIDs
  • reduce physical exertion
  • admission if T>38 0C or other risk factors
    • immunosuppressed
    • anticoag's
    • effusion
    • trauma related
    • rise in Trop
    • worsening symptoms including failure of pain management after 1/52 (with NSAIDs, colchicine)

Exercise caution adding NSAIDs to patients already on anti-platelet or anti-coag agents. Not contraindicated, depending on cause, but all risk factors must be taken into account


References include:
NEJM review of non-MI ST elevation 2003
https://litfl.com/pericarditis-ecg-library/
https://www.uptodate.com/contents/acute-pericarditis-treatment-and-prognosis
https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-15/Management-of-acute-pericarditis-treatment-and-follow-up

wiki/cardiovascular/pericarditis.txt · Last modified: 2023/04/25 14:16 by 127.0.0.1
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