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Polycystic Ovary Syndrome

Exact pathophysiology = unclear

  • often have raised testosterone
  • inappropriate gonadotrophin secretion - probably as a result of ovarian dysfunction rather than cause

Diagnostic criteria have varied over the years and vary according to body meeting! Include the following:

  • evidence of ovarian dysfunction
  • exclusion of other disorders
  • biochemical evidence of hyperandrogenism
  • ?USS evidence

Major features

  • menstrual dysfunction - usually a chronic pattern
  • anovulation
  • signs of hyperandrogenism - male hair distribution, acne
  • ~50% are obese
  • Acanthosis nigricans - possibly due to insulin resistance
  • Hypertension

treatments aimed at so-called metabolic derangements, such as anovulation, hirsutism, and menstrual irregularities.

References include:
https://emedicine.medscape.com/article/256806-overview

wiki/gynaecology/polycystic_ovary_syndrome.1592294899.txt.gz · Last modified: 2023/04/25 14:18 (external edit)
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