Dizziness

  • Vertigo
  • Disequilibrium
  • Pre-syncope
  • Light-headedness

Vertigo

  • Benign paroxysmal positional vertigo (BPPV)
    • Occurs due to problems in the heavy calcium particles (otoliths) present in the vestibular labyrinth
    • Transient, episodic vertigo is induced by head position changes.
    • most commonly post semicircular canal
    • usually self-limiting, lasting up to 6/52
    • vertigo lasts seconds - associated with movement

  • Meniere's disease
    • idiopathic by definition. Syndrome may develop secondary to trauma, infection, autoimmune disorders, endocrine disease, medications etc
    • criteria:
      • vertigo ≥2 episodes lasting 20mins up to 12/12
      • documented low to mid frequency sensorineural hearing loss
      • fluctuating hearing loss, tinnitus or pressure in affected ear
      • other causes excluded
    • vertigo lasts hours
  • Migrainous vertigo (vestibular migraine)
    • one of most common causes of vertigo
    • vestibular syndrome alongside other migraine symptoms such as headache, nausea, sensitivity to light and sound and aura
    • headache not always present
    • Criteria:
      • ≥5 episodes
      • present or PHx migraine
      • vestibular symptoms (vertigo or dizziness) lasting five minutes - 72 hours
      • the concurrence of migraine headache or other migraine associated symptoms in at least half of the episodes.
  • vestibular neuronitis
    • most likely viral with some caused by latent HSV1 reactivation in vestibular ganglia
    • vertigo, nausea, vomiting, nystagmus (Vestibular syndrome)
    • vertigo may last days, weeks
  • labyrinthitis
    • usually viral cause
    • Vestibular syndrome plus sensory deafness and tinnitus
    • vertigo may last days, weeks

Central vs Peripheral

Peripheral Vertigo • Intermittent and positional
• Vertigo stops with visual fixation
Nystagmus • delayed in onset rotatory or horizontal prominent if vertigo is present adaptive
Other • more likely to be associated with hearing loss, tinnitus
Central Vertigo • Non-positional
• does not stop with visual fixation
Nystagmus • immediate or delayed in onset rotatory, horizontal, or vertical, not adaptive
Other • more likely to have other Brainstem signs and symptoms

Self limiting acute vestibular syndrome vs stroke

HINTS tests

  • Head Impulse tests Vestibulo-ocular reflex (VOR) - disturbed in vestibular disease but not stroke
    • abnormal response is indicated by an inability to maintain fixation during head rotation with a corrective gaze shift after the head stops moving.
    • the Head Impulse involves high acceleration by low amplitude rotation of the head
  • Nystagmus
    • multi directional nystagmus has central cause
    • ie. gaze to Left causing L nystagmus and gaze to R causing nystagmus to R = central origin
  • Skew - when vertical alignment of the eyes is different. Can be made to more obvious by covering then uncovering one eye to reveal realignment

Hallpike-Dix Manoeuvre

  • sitting midway on flat exam table, instructed to look ahead at all times, examiner turns pt's 45o head to side and rapidly moving pt back to supine position with head over the edge of the table. Observe of 30sec.
    • Rotatory nystagmus is seen if the superior semicircular canal is involved (most common)
    • Horizontal nystagmus is seen if the lateral semicircular canal is involved
    • upbeating with rotatory nystagmus(top pole rotates toward under-most affected ear) is seen if post semicircular canal involved

Epley Manoeuvre

  • generally used to treat vertigo caused by BPPV involving the posterior semicircular canal, the most common type of BPPV

(View Manoeuvre)close


Management

  • Benign Paroxysmal Positional Vertigo:
    • Epley manoeuvre particlulary for post semicircular canal. Brandt-Daroff exercises
    • medication generally not helpful
  • Meniere's disease:
    • symptomatic - prochlorperazine,
    • Histamine agonits eg betahistine can be helpful (?increases circulatory flow to cochlear or my inhibit vestibular nuclei activity)
    • steroids can be helpful
  • Migrainous vertigo:
    • treatment as with other migraine types
    • difficult to differentiate from Meniere's disease as episodic dizziness with auditory auras make the two similar
    • important to have preventative med's eg amitriptyline, propranolol, candesartan, flunarizine
  • Vestibular neuronitis:
    • prochlorperazine or antihistamine
    • Cochrane review - steroids not thought to be useful immediately or long term
  • Labyrinthitis:
    • usually viral, so supportive med's only

Presyncope

  • Cardiovascular causes of dizziness include arrhythmias, myocardial infarction, carotid artery stenosis, and orthostatic hypotension
  • medications - especially but not only cardiovascular med's

Disequilibrium

  • stroke, TIA, VBI (Quick View)close
    VBI
    Vertebro-basilar Insufficiency Brainstem circulation with Cranial Nerve approximation
    1 a clinical syndrome caused by transient ischaemia of the vertebrobasilar circulation, formed by the vertebral and basilar arteries, which forms the posterior circulation of the brain.
      vertebrobasilar arteries supply the cerebellum, medulla, midbrain, and occipital cortex
      most commonly caused by atherosclerosis and/or embolism. Embolism is uncommon in vertebral arteries


    Presentation   vertigo, dizziness,syncope, drop attacks
      diplopia, visual field deficits, blindness
      ataxia, imbalance, dysmetria are common
      dysphagia, dysarthria are common
      contralateral weakness
      ipsilateral cranial N involvement when present


    Vertebral artery STROKE is associated with a variety of syndromes   Locked in syndrome
      Lateral medullary syndrome
      Internuclear ophthalmoplegia
      Cerebellar infarction
      Medial medullary syndrome
      Posterior cerebral artery occlusion




    Management
      as for TIA in general although vertebral artery TIA/stroke less commonly atherosclerotic in nature and endarterectomy/stent therefore less likely. The more distal from the brain the more likely.
      angioplasty for basilar artery disease is not uncommon
      as for TIA, prevention is key and risk stratification is central
      control of hypertension, diabetes
      management of arrhythmias
      lipid lowering
      blood thinners


    References include:
    https://radiopaedia.org/articles/vertebrobasilar-insufficiency?lang=gb
    https://www.ncbi.nlm.nih.gov/books/NBK482259/
    http://www.dizziness-and-balance.com/disorders/central/strokes/tia.html
    and acoustic neuroma need excluding
  • Poor vision commonly accompanies a feeling of imbalance
  • Parkinson disease, peripheral neuropathy, and any musculoskeletal disorders that may affect gait
  • benzodiazepines and tricyclic antidepressants
  • age

Light-headedness